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bioinformatics
6 postsBioinformatics meets prompt injection defense: the Smith-Waterman trick
An open-source technique adapts the 1981 Smith-Waterman DNA alignment algorithm to catch paraphrased prompt injections that regex and classifiers miss, boosting F1 by 34 points.
Static Search Trees: 40x Faster than Binary Search
Static search trees optimize searching of sorted data, enhancing throughput significantly.
Ancient Denisovan DNA Still Shapes Human Immunity Today
A major Yale-led study of Oceania genomes shows ancient Denisovan DNA still shapes human immunity and skeletal development today.
CommitBrief — AI code reviews, right in your terminal
A provider-agnostic, local-first CLI that reviews your staged changes, a historic range, or a whole GitHub pull request. Zero telemetry, no server. Free and open source.
commitbrief.comHow to Design a Cancer Vaccine: Neoantigens and MHC Science
UNC's PIRL lab founders discuss neoantigen detection, MHC prediction, and the engineering challenges of personalized cancer immunotherapy in a three-hour deep dive.
Sequencing Your Own DNA at Home with a MinION Device
An engineer sequenced his own genome five times at home using an Oxford Nanopore MinION, detailing costs, lab steps, and how genomic data can be queried with AI tools.
RNAValidate: CPU-only Validator for AI-Predicted 3D RNA Structures
RNAValidate checks AI-predicted 3D RNA structures against experimental data, reducing costs and identifying errors before synthesis.